Endocrine Abstracts

Alemtuzumab is an approved und well known Medication for the treatment of multiple sclerosis and it is a humanized anti-CD52 monoclonal antibody. Autoimmune diseases are the most common side effect of Alemtuzumab treatment. In our Case is after 18 Months of Alemtuzumab therapy a thyroid autoimmune disease developed. Patient with multiple sclerosis during the normal Follow up appear increased thyroid antibodies TPO 101 KU/L (normal <34) and TRAK 38.2 IU/L (normal <1.75)...

Introduction: Primary hyperparathyroidism is a disorder, characterized by autonomous overproduction of parathormone resulting in hypercalcemia. The main cause is a parathyroid adenoma. Less common etiologies are parathyroid hyperplasia and carcinoma. Primary hyperparathyroidism during pregnancy is rare and the management could be challenging. Maternal and fetal/neonatal complications occur in more than 50% of the cases.Patient: We report about a 38-year-...

Objective: The impaired awareness of hypoglycemia (IAH) affects people with type 1 diabetes and is a risk factor for severe hypoglycemia. This study aims to evaluate the association between the impaired awareness of Hypoglycemia by diabetes type 1 and the peripheral neuropathy (PNP).Methods: 276 adults with type 1 diabetes, 135 men and 141 women, were studied from Mai 2015 to January 2016 to the outpatient department of University hospital of Jena. A cro...

Objective: The impaired awareness of hypoglycemia (IAH) affects people with type 1 diabetes and is a risk factor for severe hypoglycemia. This study aims to evaluate the association between the impaired awareness of Hypoglycemia by diabetes type 1 and the peripheral neuropathy (PNP).Methods: 276 adults with type 1 diabetes, 135 men and 141 women, were studied from Mai 2015 to January 2016 to the outpatient department of University hospital of Jena. A cro...

Background and Objective: Although several epidemiological studies have been conducted, the impact of Follicle Stimulating Hormone Receptor (FSHR) polymorphisms on male infertility remains unclear. The aim of this study was to investigate the prevalence of specific FSHR Single Nucleotide Polymorphisms (SNPs) in the Greek population and associate the latter with the clinical phenotype.Patients and Methods: We enrolled 96 subjects: men with idiopathic non-...

Objective: The aim of this study was to assess prevalence of impaired awareness of hypoglycaemia (IAH) by the Gold method in people with type 1 diabetes and to compare people with and with IAH regarding metabolic control.Methods: In a cross-sectional study, we assessed IAH in 139 people with type 1 diabetes (54.1y, diabetes duration 24.0y, HbA1c 7.1%) attending the University outpatient department for endocrinology and metabolic diseases. IAH was assesse...